Functional Similarities of Protein-Coding Genes in Topologically Associating Domains and Spatially-Proximate Genomic Regions

Functional Similarities of Protein-Coding Genes in Topologically Associating Domains and Spatially-Proximate Genomic Regions

Topologically associating domains (TADs) are the structural and functional units of the genome. However, the functions of protein-coding genes existing in the same or different TADs have not been fully investigated. We compared the functional similarities of protein-coding genes existing in the same...

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Bibliographic Details
Main Authors: Chenguang Zhao, Tong Liu, Zheng Wang
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Genes
Subjects:
topologically associating domain
TAD
genome 3D structure
functions of protein-coding genes
graph autoencoder
Hi-C
Online Access:https://www.mdpi.com/2073-4425/13/3/480

Internet

https://www.mdpi.com/2073-4425/13/3/480

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