Phosphoproteomics Meets Chemical Genetics: Approaches for Global Mapping and Deciphering the Phosphoproteome

Phosphoproteomics Meets Chemical Genetics: Approaches for Global Mapping and Deciphering the Phosphoproteome

Protein kinases are important enzymes involved in the regulation of various cellular processes. To function properly, each protein kinase phosphorylates only a limited number of proteins among the thousands present in the cell. This provides a rapid and dynamic regulatory mechanism that controls bio...

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Bibliographic Details
Main Authors: Jan Jurcik, Barbara Sivakova, Ingrid Cipakova, Tomas Selicky, Erika Stupenova, Matus Jurcik, Michaela Osadska, Peter Barath, Lubos Cipak
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
protein kinase
phosphorylation
chemical genetics
conditional ATP analog-sensitive mutants
mass spectrometry
phosphoproteomics
Online Access:https://www.mdpi.com/1422-0067/21/20/7637

Internet

https://www.mdpi.com/1422-0067/21/20/7637

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