Glycogen synthase kinase 3 (GSK-3) controls T-cell motility and interactions with antigen presenting cells

Abstract Objective The threonine/serine kinase glycogen synthase kinase 3 (GSK-3) targets multiple substrates in T-cells, regulating the expression of Tbet and PD-1 on T-cells. However, it has been unclear whether GSK-3 can affect the motility of T-cells and their interactions with antigen presentin...

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Bibliographic Details
Main Authors: Alison Taylor, Christopher E. Rudd
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Research Notes
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13104-020-04971-0