Identification of Two Lpp20 CD4+ T Cell Epitopes in Helicobacter pylori-Infected Subjects

Identification of Two Lpp20 CD4+ T Cell Epitopes in Helicobacter pylori-Infected Subjects

Antigen-specific CD4+ T cells play an essential role in effective immunity against Helicobacter pylori (H. pylori) infection. Lpp20, a conserved lipoprotein of H. pylori, has been investigated as one of major protective antigens for vaccination strategies. Our previous study identified two H-2d-rest...

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Bibliographic Details
Main Authors: Yunshan Ning, Jianbin Ye, Junjie Wen, Danlin Wu, Zhongbiao Chen, Yanqing Lin, Bingxin Hu, Meiqun Luo, Jun Luo, Lijun Ning, Yan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Microbiology
Subjects:
Helicobacter pylori
Lpp20
CD4+ T cell
immunodominant epitope
HLA restriction
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.00884/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.00884/full

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