Granulocyte colony-stimulating factor (G-CSF) protects oligodendrocyte and promotes hindlimb functional recovery after spinal cord injury in rats.

BACKGROUND: Granulocyte colony-stimulating factor (G-CSF) is a protein that stimulates differentiation, proliferation, and survival of cells in the granulocytic lineage. Recently, a neuroprotective effect of G-CSF was reported in a model of cerebral infarction and we previously reported the same eff...

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Main Authors: Ryo Kadota, Masao Koda, Junko Kawabe, Masayuki Hashimoto, Yutaka Nishio, Chikato Mannoji, Tomohiro Miyashita, Takeo Furuya, Akihiko Okawa, Kazuhisa Takahashi, Masashi Yamazaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3507692?pdf=render