Translational and oncologic significance of tertiary lymphoid structures in pancreatic adenocarcinoma

Translational and oncologic significance of tertiary lymphoid structures in pancreatic adenocarcinoma

Pancreatic adenocarcinoma (PDAC) is an aggressive tumor with poor survival and limited treatment options. PDAC resistance to immunotherapeutic strategies is multifactorial, but partially owed to an immunosuppressive tumor immune microenvironment (TiME). However, the PDAC TiME is heterogeneous and ha...

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Bibliographic Details
Main Authors: Zachary Gao, Joseph Azar, Huili Zhu, Sophia Williams-Perez, Sung Wook Kang, Celia Marginean, Mark P. Rubinstein, Shalini Makawita, Hyun-Sung Lee, E. Ramsay Camp
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
tertiary lymphoid structures
pancreatic adenocarcinoma
pancreatic cancer
translational ability
immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1324093/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1324093/full

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