Functionally distinct regions of the locus Leishmania major response 15 control IgE or IFNγ level in addition to skin lesions

Functionally distinct regions of the locus Leishmania major response 15 control IgE or IFNγ level in addition to skin lesions

Leishmaniasis, a disease caused by parasites of Leishmania spp., endangers more than 1 billion people living in endemic countries and has three clinical forms: cutaneous, mucocutaneous, and visceral. Understanding of individual differences in susceptibility to infection and heterogeneity of its path...

Full description

Bibliographic Details
Main Authors: Imtissal Krayem, Yahya Sohrabi, Helena Havelková, Elena S. Gusareva, Hynek Strnad, Marie Čepičková, Valeryia Volkova, Iryna Kurey, Jarmila Vojtíšková, Milena Svobodová, Peter Demant, Marie Lipoldová
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
Leishmania major
susceptibility to infection
quantitative trait locus
advanced intercross line
recombinant mapping
bioinformatics analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1145269/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1145269/full

Similar Items