Methadone Dosage and Plasma Levels, SNPs of OPRM1 Gene and Age of First Drug Use Were Associated With Outcomes of Methadone Maintenance Treatment

Methadone Dosage and Plasma Levels, SNPs of OPRM1 Gene and Age of First Drug Use Were Associated With Outcomes of Methadone Maintenance Treatment

Objective: To explore the association between methadone dosage, plasma drug concentration, SNPs of μ-opioid receptor gene (OPRM1), ATP-binding cassette subfamily B member 1 gene (ABCB1), and methadone maintenance treatment (MMT) response.Method: A total of 240 Chinese Han participants receiving MMT...

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Bibliographic Details
Main Authors: Sufang Peng, Haifeng Jiang, Jiang Du, Shuxing Lin, Shujun Pan, Shunying Yu, Min Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Genetics
Subjects:
methadone maintenance treatment
OPRM1
ABCB1
methadone dosage
plasma drug concentration
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00450/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00450/full

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