New Investigations with Lupane Type A-Ring Azepane Triterpenoids for Antimycobacterial Drug Candidate Design

New Investigations with Lupane Type A-Ring Azepane Triterpenoids for Antimycobacterial Drug Candidate Design

Twenty lupane type A-ring azepano-triterpenoids were synthesized from betulin and its related derivatives and their antitubercular activity against <i>Mycobacterium tuberculosis</i>, mono-resistant MTB strains, and nontuberculous strains <i>Mycobacterium abscessus</i> and Myc...

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Bibliographic Details
Main Authors: Oxana Kazakova, Roxana Racoviceanu, Anastasiya Petrova, Marius Mioc, Adrian Militaru, Lucreția Udrescu, Mihai Udrescu, Adrian Voicu, Jason Cummings, Gregory Robertson, Diane J. Ordway, Richard A. Slayden, Codruța Șoica
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
triterpenoids
lupane
betulin
azepane
<i>M. tuberculosis</i>
resistant MTB strains
Online Access:https://www.mdpi.com/1422-0067/22/22/12542

Internet

https://www.mdpi.com/1422-0067/22/22/12542

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