Atorvastatin population pharmacokinetics in a real‐life setting: Influence of genetic polymorphisms and association with clinical response

Abstract The purpose of this study was to investigate the potential clinical relevance of estimating the apparent clearance (CL/F) of atorvastatin through population pharmacokinetic (PopPK) modeling with samples collected in a real‐life setting in a cohort of ambulatory patients at risk of cardiovas...

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Bibliographic Details
Main Authors: Gabriel Stillemans, Adrien Paquot, Giulio G. Muccioli, Emilia Hoste, Nadtha Panin, Anders Åsberg, Jean‐Luc Balligand, Vincent Haufroid, Laure Elens
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13185