Efficacy of Low-Dose rhGM-CSF Treatment in a Patient With Severe Congenital Neutropenia Due to CSF3R Deficiency: Case Report of a Novel Biallelic CSF3R Mutation and Literature Review

Efficacy of Low-Dose rhGM-CSF Treatment in a Patient With Severe Congenital Neutropenia Due to CSF3R Deficiency: Case Report of a Novel Biallelic CSF3R Mutation and Literature Review

This study reports the clinical manifestations, genetics, and efficacy of treatment with the efficacy of recombinant human granulocyte macrophage colony-stimulating factor (rhGM-GSF) of a 2-year-old female patient with severe congenital neutropenia (SCN) type 7 (SCN7) caused by novel biallelic mutat...

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Bibliographic Details
Main Authors: Junli Zhou, Chengjun Sun, Honglin Huang, Qiguo Zhu, Fengyun Wen, Ying Dong, Hongsheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Pediatrics
Subjects:
severe congenital neutropenia
biallelic heterozygous
CSF3R
rhGM-CSF
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.746159/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2021.746159/full

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