USP8 inhibition regulates autophagy flux and controls Salmonella infection

USP8 inhibition regulates autophagy flux and controls Salmonella infection

IntroductionUbiquitination is an important protein modification that regulates various essential cellular processes, including the functions of innate immune cells. Deubiquitinases are enzymes responsible for removing ubiquitin modification from substrates, and the regulation of deubiquitinases in m...

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Bibliographic Details
Main Authors: John Santelices, Mark Ou, Gustavo H. B. Maegawa, Kamil Hercik, Mariola J. Edelmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
deubiquitinating enzymes
deubiquitinases
Salmonella
USP8
autophagy
chemical proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1070271/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1070271/full

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