Molecular docking studies, drug-likeness and in-silico ADMET prediction of some novel β-Amino alcohol grafted 1,4,5-trisubstituted 1,2,3-triazoles derivatives as elevators of p53 protein levels

Molecular docking studies, drug-likeness and in-silico ADMET prediction of some novel β-Amino alcohol grafted 1,4,5-trisubstituted 1,2,3-triazoles derivatives as elevators of p53 protein levels

Malaria is a killer disease caused by Plasmodium falciparum and is responsible for over a million death annually. Chloroquine, quinine, pyrimethamine, proguanil, artemisinin, atovaquone, and mefloquine are different kinds of drugs employed to treat the disease, but due to increased drug resistance t...

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Bibliographic Details
Main Authors: Zakari Ya'u Ibrahim, Adamu Uzairu, Gideon Shallangwa, Stephen Abechi
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Scientific African
Subjects:
Molecular docking
Drug-likeness
ADMET properties
β-Amino alcohol grafted 1,4,5-trisubstituted 1,2,3-triazoles
and p53 protein
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227620303082

Internet

http://www.sciencedirect.com/science/article/pii/S2468227620303082

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