Discovery and analysis of evolutionarily conserved intronic splicing regulatory elements.

Knowledge of the functional cis-regulatory elements that regulate constitutive and alternative pre-mRNA splicing is fundamental for biology and medicine. Here we undertook a genome-wide comparative genomics approach using available mammalian genomes to identify conserved intronic splicing regulatory...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Gene W Yeo, Eric L Van Nostrand, Tiffany Y Liang
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Public Library of Science (PLoS) 2007-05-01
Σειρά:PLoS Genetics
Διαθέσιμο Online:http://europepmc.org/articles/PMC1877881?pdf=render