Mechanistic insight into the induction of cellular immune responses by encapsulated and admixed archaeosome-based vaccine formulations

Mechanistic insight into the induction of cellular immune responses by encapsulated and admixed archaeosome-based vaccine formulations

Archaeosomes are liposomes formulated using total polar lipids (TPLs) or semi-synthetic glycolipids derived from archaea. Conventional archaeosomes with entrapped antigen exhibit robust adjuvant activity as demonstrated by increased antigen-specific humoral and cell-mediated responses and enhanced p...

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Bibliographic Details
Main Authors: Gerard Agbayani, Yimei Jia, Bassel Akache, Vandana Chandan, Umar Iqbal, Felicity C. Stark, Lise Deschatelets, Edmond Lam, Usha D. Hemraz, Sophie Régnier, Lakshmi Krishnan, Michael J. McCluskie
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
archaeosome
adjuvant
sulfated lactosyl archaeol
sla
archaeol
glycolipid
vaccine
Online Access:http://dx.doi.org/10.1080/21645515.2020.1788300

Internet

http://dx.doi.org/10.1080/21645515.2020.1788300

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