Ferrochelatase is a therapeutic target for ocular neovascularization

Ferrochelatase is a therapeutic target for ocular neovascularization

Abstract Ocular neovascularization underlies major blinding eye diseases such as “wet” age‐related macular degeneration (AMD). Despite the successes of treatments targeting the vascular endothelial growth factor (VEGF) pathway, resistant and refractory patient populations necessitate discovery of ne...

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Bibliographic Details
Main Authors: Halesha D Basavarajappa, Rania S Sulaiman, Xiaoping Qi, Trupti Shetty, Sardar Sheik Pran Babu, Kamakshi L Sishtla, Bit Lee, Judith Quigley, Sameerah Alkhairy, Christian M Briggs, Kamna Gupta, Buyun Tang, Mehdi Shadmand, Maria B Grant, Michael E Boulton, Seung‐Yong Seo, Timothy W Corson
Format: Article
Language:English
Published: Springer Nature 2017-04-01
Series:EMBO Molecular Medicine
Subjects:
age‐related macular degeneration
angiogenesis
ferrochelatase
griseofulvin
heme synthesis
Online Access:https://doi.org/10.15252/emmm.201606561

Internet

https://doi.org/10.15252/emmm.201606561

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