Somatostatin Containing δ-Cell Number Is Reduced in Type-2 Diabetes

Somatostatin Containing δ-Cell Number Is Reduced in Type-2 Diabetes

Recent developments suggest that increased glucagon and decreased somatostatin secretion from the pancreas contribute to hyperglycaemia in type-2 diabetes (T2D) patients. There is a huge need to understand changes in glucagon and somatostatin secretion to develop potential anti-diabetic drugs. To fu...

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Bibliographic Details
Main Authors: Lakshmi Kothegala, Caroline Miranda, Meetu Singh, Jean-Philippe Krieger, Nikhil R. Gandasi
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Type-2-Diabetes
islet-hormone secretion
multi-photon imaging
Confocal microscopy
pancreatic islets
Online Access:https://www.mdpi.com/1422-0067/24/4/3449

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https://www.mdpi.com/1422-0067/24/4/3449

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