The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation

The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation

Background A hallmark of heart failure is cardiac fibrosis, which results from the injury‐induced differentiation response of resident fibroblasts to myofibroblasts that deposit extracellular matrix. During myofibroblast differentiation, fibroblasts progress through polarization stages of early proi...

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Bibliographic Details
Main Authors: Nicholas W. Chavkin, Soichi Sano, Ying Wang, Kosei Oshima, Hayato Ogawa, Keita Horitani, Miho Sano, Susan MacLauchlan, Anders Nelson, Karishma Setia, Tanvi Vippa, Yosuke Watanabe, Jeffrey J. Saucerman, Karen K. Hirschi, Noyan Gokce, Kenneth Walsh
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
fibroblasts
fibrosis
heart failure
inflammation
myocardial inflammation
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.019904

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.019904

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