An improved method for the covalent attachment of glycolipids to solid supports and macromolecules.

A simplified method is presented for the oxidation of the olefinic bond of the sphingosine moiety of glycosphingolipids to a carboxyl group. Coupling of such “glycolipid acids” to glass beads, agarose gels, proteins, and polyacrylic hydrazide polymers is described. Solid supports and macromolecules...

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Bibliographic Details
Main Authors: W W Young, Jr, R A Laine, S Hakomori
Format: Article
Language:English
Published: Elsevier 1979-02-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520406418