Novel Highly Pathogenic Avian A(H5N2) and A(H5N8) Influenza Viruses of Clade 2.3.4.4 from North America Have Limited Capacity for Replication and Transmission in Mammals

ABSTRACT Highly pathogenic influenza A(H5N8) viruses from clade 2.3.4.4 were introduced to North America by migratory birds in the fall of 2014. Reassortment of A(H5N8) viruses with avian viruses of North American lineage resulted in the generation of novel A(H5N2) viruses with novel genotypes. Thro...

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Main Authors: Bryan S. Kaplan, Marion Russier, Trushar Jeevan, Bindumadhav Marathe, Elena A. Govorkova, Charles J. Russell, Mia Kim-Torchetti, Young Ki Choi, Ian Brown, Takehiko Saito, David E. Stallknecht, Scott Krauss, Richard J. Webby
Format: Article
Language:English
Published: American Society for Microbiology 2016-04-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00003-16