The Early Events That Initiate β-Amyloid Aggregation in Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by the development of amyloid plaques and neurofibrillary tangles (NFTs) consisting of aggregated β-amyloid (Aβ) and tau, respectively. The amyloid hypothesis has been the predominant framework for research in AD for over two decades. According to this hypot...

Full description

Bibliographic Details
Main Authors: Xingyu Zhang, Zhihui Fu, Lanxia Meng, Mingyang He, Zhentao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00359/full