Somatic Copy-Number Alterations in Plasma Circulating Tumor DNA from Advanced EGFR-Mutated Lung Adenocarcinoma Patients

Somatic Copy-Number Alterations in Plasma Circulating Tumor DNA from Advanced EGFR-Mutated Lung Adenocarcinoma Patients

Background: To assess the clinical relevance of genome-wide somatic copy-number alterations (SCNAs) in plasma circulating tumor DNA (ctDNA) from advanced epidermal growth factor receptor (<i>EGFR</i>)-mutated lung adenocarcinoma patients. Methods: We included 43 patients with advanced &l...

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Bibliographic Details
Main Authors: Anna Buder, Ellen Heitzer, Julie Waldispühl-Geigl, Sabrina Weber, Tina Moser, Maximilian J. Hochmair, Klaus Hackner, Peter Errhalt, Ulrike Setinek, Martin Filipits
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomolecules
Subjects:
NSCLC
osimertinib
somatic copy-number alterations
ctDNA
<i>EGFR</i> mutations
Online Access:https://www.mdpi.com/2218-273X/11/5/618

Internet

https://www.mdpi.com/2218-273X/11/5/618

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