Dual Effects of Cell Free Supernatants from Lactobacillus acidophilus and Lactobacillus rhamnosus GG in Regulation of MMP-9 by Up-Regulating TIMP-1 and Down-Regulating CD147 in PMADifferentiated THP-1 Cells

Objective: Recent studies have reported dysregulated expression of matrix metalloproteinases (MMPs), especially MMP-2, MMP-9, tissue inhibitor of metalloproteinase-1, -2 (TIMP-1, TIMP-2), and extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in activated macrophages of patients with i...

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Bibliographic Details
Main Authors: Faezeh Maghsood, Abbas Mirshafiey, Mohadese M. Farahani, Mohammad Hossein Modarressi, Parvaneh Jafari, Elahe Motevaseli
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2017-11-01
Series:Cell Journal
Subjects:
Online Access:http://celljournal.org/journal/article/16338/download