A LETM2-Regulated PI3K-Akt Signaling Axis Reveals a Prognostic and Therapeutic Target in Pancreatic Cancer

A LETM2-Regulated PI3K-Akt Signaling Axis Reveals a Prognostic and Therapeutic Target in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the highest mortalities malignant tumors, which is characterized by difficult diagnosis, rapid progression and high recurrence rate. Nevertheless, PDAC responds poorly to conventional therapies, which highlights the urgency to identify novel prognost...

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Bibliographic Details
Main Authors: Shurui Zhou, Ziyi Zhong, Yanzong Lu, Yunlong Li, Hanming Yao, Yue Zhao, Tairan Guo, Kege Yang, Yaqing Li, Shaojie Chen, Kaihong Huang, Guoda Lian
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
LETM2
pan-cancer analysis
pancreatic ductal adenocarcinoma
PI3K-Akt pathway
tumor progression
Online Access:https://www.mdpi.com/2072-6694/14/19/4722

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https://www.mdpi.com/2072-6694/14/19/4722

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