Inverse relationship between tumour proliferation markers and connexin expression in a malignant cardiac tumour originating from mesenchymal stem cell engineered tissue in a rat in-vivo model.

Inverse relationship between tumour proliferation markers and connexin expression in a malignant cardiac tumour originating from mesenchymal stem cell engineered tissue in a rat in-vivo model.

Background: Recently, we demonstrated the beneficial effects of engineered heart tissues for the treatment of dilated cardiomyopathy in rats. For further development of this technique we started to produce engineered tissue (ET) from mesenchymal stem cells. Interestingly, we observed a malignant tum...

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Bibliographic Details
Main Authors: Cathleen eSpath, Franziska eSchlegel, Sergey eLeontyev, Friedrich Wilhelm Mohr, Stefan eDhein
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Pharmacology
Subjects:
Connexins
Gap Junctions
Sarcoma, Experimental
proliferation
tumour
Cx43
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00042/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00042/full

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