Application of physiologically based pharmacokinetic modeling in predicting drug–drug interactions for sarpogrelate hydrochloride in humans

Application of physiologically based pharmacokinetic modeling in predicting drug–drug interactions for sarpogrelate hydrochloride in humans

Jee Sun Min,1 Doyun Kim,1 Jung Bae Park,1 Hyunjin Heo,1 Soo Hyeon Bae,2 Jae Hong Seo,1 Euichaul Oh,1 Soo Kyung Bae1 1Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon, 2Department of Pharmacology, College of Medicine, The Cathol...

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Bibliographic Details
Main Authors: Min JS, Kim D, Park JB, Heo H, Bae SH, Seo JH, Oh E, Bae SK
Format: Article
Language:English
Published: Dove Medical Press 2016-09-01
Series:Drug Design, Development and Therapy
Subjects:
Sarpogrelate hydrochloride
M-1
CYP2D6 inhibition
PBPK modeling
Drug-drug interaction
Online Access:https://www.dovepress.com/application-of-physiologically-based-pharmacokinetic-modeling-in-predi-peer-reviewed-article-DDDT

Internet

https://www.dovepress.com/application-of-physiologically-based-pharmacokinetic-modeling-in-predi-peer-reviewed-article-DDDT

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