Deciphering the possible role of MmpL7 efflux pump in SQ109 resistance in Mycobacterium tuberculosis

Deciphering the possible role of MmpL7 efflux pump in SQ109 resistance in Mycobacterium tuberculosis

Abstract Background SQ109 is a promising candidate drug for the treatment of patients with drug-resistant tuberculosis (DR-TB). The purpose of this study was to investigate the activity of SQ109 against clinical isolates of Mycobacterium tuberculosis (MTB) from patients with multidrug-resistant TB (...

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Bibliographic Details
Main Authors: Wei Jing, Fuzhen Zhang, Yuanyuan Shang, Wenhui Shi, Cong Yao, Xuxia Zhang, Naihui Chu, Jie Lu, Jinfeng Yuan
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Mycobacterium tuberculosis
SQ109
Susceptibility
MmpL7
Online Access:https://doi.org/10.1186/s12941-024-00746-8

Internet

https://doi.org/10.1186/s12941-024-00746-8

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