Analysis of Regulatory Mechanism of AcrB and CpxR on Colistin Susceptibility Based on Transcriptome and Metabolome of Salmonella Typhimurium

Analysis of Regulatory Mechanism of AcrB and CpxR on Colistin Susceptibility Based on Transcriptome and Metabolome of Salmonella Typhimurium

ABSTRACT With the increasing and inappropriate use of colistin, the emerging colistin-resistant isolates have been frequently reported during the last few decades. Therefore, new potential targets and adjuvants to reverse colistin resistance are urgently needed. Our previous study has confirmed a ma...

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Bibliographic Details
Main Authors: Ya-Jun Zhai, Pei-Yi Liu, Xing-Wei Luo, Jun Liang, Ya-Wei Sun, Xiao-Die Cui, Dan-Dan He, Yu-Shan Pan, Hua Wu, Gong-Zheng Hu
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
colistin susceptibility
AcrB
CpxR
transcriptome
metabolome
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00530-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.00530-23

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