Modulation of Cellular Function by the Urokinase Receptor Signalling: A Mechanistic View

Modulation of Cellular Function by the Urokinase Receptor Signalling: A Mechanistic View

Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease urokinase (uPA), converting plasminogen into plasmin, a broad spectrum protease, active on most extracellular matrix compon...

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Bibliographic Details
Main Authors: Daniela Alfano, Paola Franco, Maria Patrizia Stoppelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
urokinase receptor
cell migration
epithelial mesenchyme transition
stemness
cell differentiation
virus infection
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.818616/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.818616/full

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