Unveiling the functional epitopes of cobra venom cytotoxin by immunoinformatics and epitope-omic analyses

Abstract Approximate 70% of cobra venom is composed of cytotoxin (CTX), which is responsible for the dermonecrotic symptoms of cobra envenomation. However, CTX is generally low in immunogenicity, and the antivenom is ineffective in attenuating its in vivo toxicity. Furthermore, little is known about...

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Bibliographic Details
Main Authors: Jia Jin Hiu, Jared Kah Yin Fung, Hock Siew Tan, Michelle Khai Khun Yap
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39222-2