Human IgM<sup>hi</sup>CD300a<sup>+</sup> B Cells Are Circulating Marginal Zone Memory B Cells That Respond to Pneumococcal Polysaccharides and Their Frequency Is Decreased in People Living with HIV

Human IgM<sup>hi</sup>CD300a<sup>+</sup> B Cells Are Circulating Marginal Zone Memory B Cells That Respond to Pneumococcal Polysaccharides and Their Frequency Is Decreased in People Living with HIV

CD300a is differentially expressed among B cell subsets, although its expression in immunoglobulin (Ig)M<sup>+</sup> B cells is not well known. We identified a B cell subset expressing CD300a and high levels of IgM (IgM<sup>hi</sup>CD300a<sup>+</sup>). The results...

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Bibliographic Details
Main Authors: Joana Vitallé, Olatz Zenarruzabeitia, Aitana Merino-Pérez, Iñigo Terrén, Ane Orrantia, Arantza Pacho de Lucas, José A. Iribarren, Lucio J. García-Fraile, Luz Balsalobre, Laura Amo, Belén de Andrés, Francisco Borrego
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
CD300
CD300a
IgM
IgD
B cell
memory
Online Access:https://www.mdpi.com/1422-0067/24/18/13754

Internet

https://www.mdpi.com/1422-0067/24/18/13754

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