Butyrate suppresses experimental necrotizing enterocolitis–induced brain injury in mice

BackgroundNecrotizing enterocolitis (NEC) is a devastating disease in premature infants, and 50% of infants with surgical NEC develop neurodevelopmental defects. The mechanisms by which NEC-induced cytokine release and activation of inflammatory cells in the brain mediate neuronal injury, and whethe...

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Bibliographic Details
Main Authors: Maribel Martinez, Wei Yu, Heather L. Menden, Tianhua Lei, Paula Monaghan-Nichols, Venkatesh Sampath
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1284085/full