Copper exposure induces ovarian granulosa cell apoptosis by activating the caspase-dependent apoptosis signaling pathway and corresponding changes in microRNA patterns

Copper exposure induces ovarian granulosa cell apoptosis by activating the caspase-dependent apoptosis signaling pathway and corresponding changes in microRNA patterns

Environmental copper (Cu) contamination is a complex worldwide public health problem. However, information on the effects of Cu pollution on human reproduction is limited. Although our previous studies have indicated that Cu exposure disrupts ovarian folliculogenesis, the underlying mechanism needs...

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Bibliographic Details
Main Authors: Yiqin Chen, Fangyuan Guan, Panlin Wang, Weili Liu, Wenhui Zhang, Han Sun, Lingling Zhu, Yanxin Huang, Yan Sun, Wenxiang Wang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Copper
Apoptosis
Ovarian granulosa cells
MiRNAs
Epigenetic
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323009181

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http://www.sciencedirect.com/science/article/pii/S0147651323009181

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