Development of single-cell-level microfluidic technology for long-term growth visualization of living cultures of Mycobacterium smegmatis

Abstract Analysis of growth and death kinetics at single-cell resolution is a key step in understanding the complexity of the nonreplicating growth phenotype of the bacterial pathogen Mycobacterium tuberculosis. Here, we developed a single-cell-resolution microfluidic mycobacterial culture device th...

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Bibliographic Details
Main Authors: Han Wang, Gloria M. Conover, Song-I Han, James C. Sacchettini, Arum Han
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-021-00262-1