Non-contrast assessment of blood-brain barrier permeability to water in mice: An arterial spin labeling study at cerebral veins

Non-contrast assessment of blood-brain barrier permeability to water in mice: An arterial spin labeling study at cerebral veins

Blood-brain barrier (BBB) plays a critical role in protecting the brain from toxins and pathogens. However, in vivo tools to assess BBB permeability are scarce and often require the use of exogenous contrast agents. In this study, we aimed to develop a non-contrast arterial-spin-labeling (ASL) based...

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Bibliographic Details
Main Authors: Zhiliang Wei, Hongshuai Liu, Zixuan Lin, Minmin Yao, Ruoxuan Li, Chang Liu, Yuguo Li, Jiadi Xu, Wenzhen Duan, Hanzhang Lu
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:NeuroImage
Subjects:
Blood-brain barrier
Permeability surface-area product
Water extraction
Arterial spin labeling
Mouse
MRI
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811923000198

Internet

http://www.sciencedirect.com/science/article/pii/S1053811923000198

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