ST09, A Novel Curcumin Derivative, Blocks Cell Migration by Inhibiting Matrix Metalloproteases in Breast Cancer Cells and Inhibits Tumor Progression in EAC Mouse Tumor Models

ST09, A Novel Curcumin Derivative, Blocks Cell Migration by Inhibiting Matrix Metalloproteases in Breast Cancer Cells and Inhibits Tumor Progression in EAC Mouse Tumor Models

Purpose: Curcumin is known for its anticancer and migrastatic activity in various cancers, including breast cancer. Newer curcumin derivatives are being explored to overcome limitations of curcumin like low bioavailability, stability, and side effects due to its higher dose. In this study, the synth...

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Bibliographic Details
Main Authors: Snehal Nirgude, Raghunandan Mahadeva, Jinsha Koroth, Sujeet Kumar, Kothanahally S. Sharath Kumar, Vidya Gopalakrishnan, Subhas S Karki, Bibha Choudhary
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
MDA-MB-231
MCF7
EAC mouse tumor model
apoptosis
migrastatic
immunity boosting cancer therapeutics
Online Access:https://www.mdpi.com/1420-3049/25/19/4499

Internet

https://www.mdpi.com/1420-3049/25/19/4499

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