“Modulating Phosphoinositide Profiles as a Roadmap for Treatment in Acute Myeloid Leukemia”

“Modulating Phosphoinositide Profiles as a Roadmap for Treatment in Acute Myeloid Leukemia”

Polyphosphoinositides (PPIns) and their modulating enzymes are involved in regulating many important cellular functions including proliferation, differentiation or gene expression, and their deregulation is involved in human diseases such as metabolic syndromes, neurodegenerative disorders and cance...

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Bibliographic Details
Main Authors: Stefano Ratti, Camilla Evangelisti, Sara Mongiorgi, Alessia De Stefano, Antonietta Fazio, Francesca Bonomini, Matilde Y. Follo, Irene Faenza, Lucia Manzoli, Bhavwanti Sheth, Magdalena C. Vidalle, Scott T. Kimber, Nullin Divecha, Lucio Cocco, Roberta Fiume
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
phosphoinositides
PLCB1
PI3K
PIP4K
AML
epigenetic
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.678824/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.678824/full

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