4335 Role of PSD95 and nNOS interaction in gene regulation following fear conditioning and implications for molecular mechanisms underlying PTSD

OBJECTIVES/GOALS: Normal fear learning produces avoidance behavior that promotes survival, but excessive and persistent fear after trauma can lead to development of phobias and post-traumatic stress disorder (PTSD). Our goal is to understand the mechanism and identify novel genetic targets underlyin...

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Bibliographic Details
Main Authors: Jheel Patel, Erik Dustrude, Melissa Haulcomb, Liangping Li, Guanglong Jiang, Yunlong Liu, Yvonne Lai, Andrei Molosh, Anantha Shekhar
Format: Article
Language:English
Published: Cambridge University Press 2020-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866120000904/type/journal_article