Epigenetic silencing of RNF144A expression in breast cancer cells through promoter hypermethylation and MBD4

Abstract Emerging evidence shows that ring finger protein 144A (RNF144A), a poorly characterized member of the Ring‐between‐Ring (RBR) family of E3 ubiquitin ligases, is a potential tumor suppressor gene. However, its regulatory mechanism in breast cancer remains undefined. Here, we report that RNF1...

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Bibliographic Details
Main Authors: Ye Zhang, Yin‐Long Yang, Fang‐Lin Zhang, Xiao‐Hong Liao, Zhi‐Min Shao, Da‐Qiang Li
Format: Article
Language:English
Published: Wiley 2018-04-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.1324