The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation
<p>Mitochondria are the major reactive oxygen species (ROS) – generating sites in mammalian cells. Blockade of complexes in the electron transport chain (ETC) increases the leakage of single electrons to O<sub>2</sub> and therefore increases ROS levels. Complexes I and II...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Ivyspring International Publisher
2007-01-01
|
Series: | International Journal of Biological Sciences |
Online Access: | http://www.biolsci.org/v03p0335.htm |