Metabolic modulation: Pneumocystis phosphoglucomutase is a target influencing host recognition
Herein, this manuscript explores the significance of the phosphoglucomutase (PGM) enzyme in Pneumocystis spp., focusing on its role in fungal surface mannoprotein formation. Through expression of the Pneumocystis murina Pmpgm2 in a Saccharomyces cerevisiae pgm2Δ strain, we demonstrate restoration of...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-06-01
|
Series: | The Cell Surface |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2468233024000057 |