MicroRNAs miR-16 and miR-519 control meningioma cell proliferation via overlapping transcriptomic programs shared with the RNA-binding protein HuR

MicroRNAs miR-16 and miR-519 control meningioma cell proliferation via overlapping transcriptomic programs shared with the RNA-binding protein HuR

IntroductionMeningiomas are the most common type of primary central nervous system tumors. In about 80% cases, these tumors are benign and grow very slowly, but the remainder 20% can unlock higher proliferation rates and become malignant. In this study we examined two miRs, miR-16 and miR-519, and e...

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Bibliographic Details
Main Authors: Sébastien Hergalant, Jean-Matthieu Casse, Abderrahim Oussalah, Rémi Houlgatte, Déborah Helle, Fabien Rech, Laurent Vallar, Jean-Louis Guéant, Jean-Michel Vignaud, Shyue-Fang Battaglia-Hsu, Guillaume Gauchotte
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
miR-16
miR-519
microRNA
HuR
proliferation
tumorigenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1158773/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1158773/full

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