CAR-T manufactured from frozen PBMC yield efficient function with prolonged in vitro production
Chimeric antigen receptor (CAR)-T cells are engineered to identify and eliminate cells expressing a target antigen. Current manufacturing protocols vary between commercial CAR-T cell products warranting an assessment of these methods to determine which approach optimally balances successful manufact...
Main Authors: | , , , , , , , |
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פורמט: | Article |
שפה: | English |
יצא לאור: |
Frontiers Media S.A.
2022-09-01
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סדרה: | Frontiers in Immunology |
נושאים: | |
גישה מקוונת: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.1007042/full |