Prospective Evaluation of a Circulating Tumor Cell Sensitivity Profile to Predict Response to Cisplatin Chemotherapy in Metastatic Breast Cancer Patients

Prospective Evaluation of a Circulating Tumor Cell Sensitivity Profile to Predict Response to Cisplatin Chemotherapy in Metastatic Breast Cancer Patients

BackgroundCisplatin (cDDP) has regained interest for metastatic breast cancer (MBC) patients, given the platinum sensitivity in subtypes and better manageable toxicity. Here, the primary aim was to determine whether molecular characteristics of circulating tumor cells (CTCs) could identify patients...

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Bibliographic Details
Main Authors: I. E. de Kruijff, A. M. Sieuwerts, N. Beije, W. J. C. Prager - van der Smissen, L. Angus, C. M. Beaufort, M. N. Van, E. Oomen - de Hoop, A. Jager, P. Hamberg, F. E. de Jongh, J. Kraan, J. W. M. Martens, S. Sleijfer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
metastatic breast cancer
circulating tumor cells (CTCs)
mRNA profile
cisplatin
cDDP
resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.697572/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.697572/full

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