A Novel Translational Ovine Pulmonary Adenocarcinoma Model for Human Lung Cancer

A Novel Translational Ovine Pulmonary Adenocarcinoma Model for Human Lung Cancer

In vitro cell line and in vivo murine models have historically dominated pre-clinical cancer research. These models can be expensive and time consuming and lead to only a small percentage of anti-cancer drugs gaining a license for human use. Large animal models that reflect human disease have high t...

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Bibliographic Details
Main Authors: Mark E. Gray, Paul Sullivan, Jamie R. K. Marland, Stephen N. Greenhalgh, James Meehan, Rachael Gregson, R. Eddie Clutton, Chris Cousens, David J. Griffiths, Alan Murray, David Argyle
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Oncology
Subjects:
human lung cancer
ovine pulmonary adenocarcinoma
novel translational lung cancer model
pre-clinical research
computed tomography-guided sensor implantation
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00534/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00534/full

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