Inhibition of chromatin condensation disrupts planar cell migration

ABSTRACTCell migration involves the actin cytoskeleton, and recently recognized nuclear involvement. In this study, we explore the impact of chromatin remodeling on cell migration using NIH 3T3 cells and a scratch wound assay subjected to pharmacological interventions. We inhibit histone deacetylase...

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Bibliographic Details
Main Authors: Jack Forman, Briar Hine, Samantha Kaonis, Soham Ghosh
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Nucleus
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19491034.2024.2325961