CRISPR Co-Editing Strategy for Scarless Homology-Directed Genome Editing

CRISPR Co-Editing Strategy for Scarless Homology-Directed Genome Editing

The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 has revolutionized genome editing by providing a simple and robust means to cleave specific genomic sequences. However, introducing templated changes at the targeted site usually requires homology-directed repair (HDR), activ...

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Bibliographic Details
Main Authors: Nina Reuven, Julia Adler, Nadav Myers, Yosef Shaul
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
gene targeting
CRISPR/Cas9
genome editing
endogenous mutagenesis in cell lines
co-editing
scarless selection
Online Access:https://www.mdpi.com/1422-0067/22/7/3741

Internet

https://www.mdpi.com/1422-0067/22/7/3741

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