Discovery of SARS-CoV-2 RNA-dependent-RNA-polymerase (RdRp) Inhibitor from Sambiloto (Andrographis paniculata) Based on Molecular Docking and ADMET Prediction Approach

Discovery of SARS-CoV-2 RNA-dependent-RNA-polymerase (RdRp) Inhibitor from Sambiloto (Andrographis paniculata) Based on Molecular Docking and ADMET Prediction Approach

The rapid spread of the coronavirus disease 2019 (COVID-19) has led to the development of therapeutic inhibitor drug of SARS-CoV-2, which can inhibit the viral enzyme RNA-dependent-RNA-polymerase (RdRp), thereby preventing the replication, transcription, and synthesis of RNA virus in the host cells....

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Bibliographic Details
Main Authors: Dina Ahsana, Rizki Rahmadi Pratama, Alfisyahriatunnida Meily, Andika
Format: Article
Language:English
Published: Universitas Indonesia 2022-08-01
Series:Pharmaceutical Sciences and Research
Subjects:
adrographis paniculata
andrographolactone
rna-dependent-rna-polymerase (rdrp)
sars-cov-2
Online Access:https://scholarhub.ui.ac.id/psr/vol9/iss2/3/

Internet

https://scholarhub.ui.ac.id/psr/vol9/iss2/3/

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