ALS/FTD: Evolution, Aging, and Cellular Metabolic Exhaustion

Amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) are neurodegenerations with evolutionary underpinnings, expansive clinical presentations, and multiple genetic risk factors involving a complex network of pathways. This perspective considers the complex cellular pathology of aging...

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Bibliographic Details
Main Authors: Robert David Henderson, Kasper Planeta Kepp, Andrew Eisen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.890203/full