ALS/FTD: Evolution, Aging, and Cellular Metabolic Exhaustion

ALS/FTD: Evolution, Aging, and Cellular Metabolic Exhaustion

Amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) are neurodegenerations with evolutionary underpinnings, expansive clinical presentations, and multiple genetic risk factors involving a complex network of pathways. This perspective considers the complex cellular pathology of aging...

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Bibliographic Details
Main Authors:	Robert David Henderson, Kasper Planeta Kepp, Andrew Eisen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Series:	Frontiers in Neurology
Subjects:	motor neuron disease amyotrophic lateral sclerosis evolution protein metabolism aging
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2022.890203/full

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